Favrille Announces Data From Phase 2 Clinical Trial of FavId for Indolent B-Cell Non-Hodgkin's Lymphoma in Europe
Favrille, Inc. (NASDAQ:FVRL) , a biopharmaceutical company developing patient-specific, active immunotherapies for the treatment of cancer, announced interim data from a Phase 2 clinical trial of FavId in patients with indolent B-cell non-Hodgkin's lymphoma (NHL). The data were reported at the Congress of the European Hematology Association in Vienna on Saturday.
"We are encouraged by the preliminary results from this trial, which included patients with differing forms of indolent B-cell NHL," said Emanuele Zucca, M.D., co-investigator and Head of the Lymphoma Unit at the Oncology Institute of Southern Switzerland. "We are also encouraged by the feasibility of administering a patient-specific active immunotherapy, manufactured in the U.S., in patients in Europe."
A copy of Dr. Zucca's presentation is now available on Favrille's website at http://www.favrille.com/.
This ongoing Phase 2 clinical trial is open to patients with various indolent forms of B-cell NHL who are either treatment-naïve, relapsed or refractory following prior chemotherapy, or relapsed following a prior response to Rituxan. The trial is expected to enroll 15 patients, but enrollment may be expanded if activity is seen in any specific patient subset.
About FavId
FavId is a patient-specific, Id/KLH active immunotherapy for the treatment of B-cell NHL. Favrille completed enrollment in its pivotal Phase 3 clinical trial of FavId following Rituxan induction therapy in patients with follicular B-cell NHL in January 2006. The trigger for the analysis of the primary endpoint in the trial, time to tumor progression (TTP), is based on a specific number of patients reaching disease progression. This is currently projected to occur around the end of 2007. The Company has a Special Protocol Assessment from the U.S. Food and Drug Administration (FDA) for its Phase 3 trial, and has also received Fast Track designation for FavId from the FDA.
About Favrille, Inc.
Favrille, Inc. is a biopharmaceutical company focused on the development and commercialization of targeted immunotherapies for the treatment of cancer and other diseases of the immune system. The Company's lead product candidate, FavId, is based upon unique genetic information extracted from a patient's tumor. FavId is currently under investigation in a pivotal Phase 3 clinical trial for patients with follicular B-cell NHL and Phase 2 clinical trials in other B-cell NHL indications. The Company is developing additional applications based on its immunotherapy expertise and proprietary cost- effective manufacturing technology, including a second product candidate, FAV-201, for the treatment of cutaneous T-cell lymphoma.