Hollis-Eden Pharmaceuticals to Present at Rodman & Renshaw 5th Annual Global Healthcare Conference

Hollis-Eden Pharmaceuticals, Inc. (NASDAQ:HEPH) today announced that it will present at the Rodman & Renshaw 5th Annual Global Healthcare Conference in Monte Carlo, Monaco on May 20, 2008, 4:40 a.m. EDT (10:40 a.m. Central European Summer Time). Richard B. Hollis, Chairman and Chief Executive Officer, will be presenting. A live webcast will be available from this conference, and may be accessed under “Event Calendar” on the Investors section of Hollis-Eden’s website at www.holliseden.com. The webcast will be archived at the Company’s website for 30 days.

Hollis-Eden Pharmaceuticals, Inc.

Hollis-Eden Pharmaceuticals, Inc. is a world leader in the development of a proprietary class of adrenal steroid hormones as novel pharmaceuticals for human health. Through its Hormonal Signaling Technology Platform, Hollis-Eden is developing a new series of small molecule compounds that are metabolites or synthetic analogs of endogenous hormones derived by the adrenal glands from the body’s most abundant circulating adrenal steroid. These steroid hormones, designed to restore the biological activity of cellular signaling pathways disrupted by disease and aging, have been demonstrated in humans to possess several properties with potential therapeutic benefit -- they regulate innate and adaptive immunity, reduce nonproductive inflammation and stimulate cell proliferation. The Company’s clinical drug development candidates include TRIOLEX (HE3286), a next-generation compound currently in clinical trials for the treatment of type 2 diabetes, ulcerative colitis and being prepared for clinical trials in rheumatoid arthritis, and APOPTONE (HE3235), a next-generation compound being prepared for clinical trials in cancer. In addition to these clinical development candidates, Hollis-Eden has an active research program that is generating additional new clinical leads that are being further evaluated in preclinical models of a number of different diseases. For more information on Hollis-Eden, visit the Company's website at www.holliseden.com.