WILMINGTON, Mass. -- (BUSINESS WIRE) -- Kapa Biosystems, Inc., a leading supplier of reagents for the life science market, today announced that its KAPA Library Preparation Kits have been selected for use in the 100K Foodborne Pathogen Genome Project, an innovative collaboration between the U.S. Food and Drug Administration (FDA), the University of California, Davis, Agilent Technologies Inc., and the Centers for Disease Control and Prevention (CDC). The five-year effort aims to create the largest public database of 100,000 foodborne pathogen genomes to help speed the identification of bacteria responsible for foodborne outbreaks and significantly reduce the typical public health response time to outbreaks from weeks to days using next-generation sequencing platforms.
Researchers will use the KAPA Library Preparation Kit to construct high-quality DNA fragment libraries for next-generation sequencing on Illumina® platforms to unlock the genomes of important foodborne pathogens such as Salmonella, Listeria, and E. coli. The KAPA kit employs optimally formulated and evolved enzymes combined with a fine-tuned protocol to achieve highly diverse libraries and improved sequence quality.
“The 100K Foodborne Pathogen Genome Project is creating a genomic database 100 times larger than what is currently available in the public domain. This information will revolutionize our basic understanding of these disease-causing microorganisms that occur and persist in animals and the food supply, with the aim of increasing public safety,” said Bart C. Weimer, Ph.D., Project Director and Professor of Population Health & Reproduction, School of Veterinary Medicine at UC Davis. “Microbes by nature can be difficult to sequence as they often contain a high percentage of AT- and GC-rich genomic content. Uniform sequencing coverage is crucial to building a high quality genomic database, and it is important that we use reagents that consistently produce low-bias, high-yield libraries that enable us to maximize the genomic information we obtain from each sample.”
All of the foodborne pathogen genomic information will be stored in a free and public database at National Institutes of Health (NIH)’s National Center for Biotechnology Information. Open access to the database will allow researchers to develop tests that can identify the type of bacteria present in a sample within a matter of days or hours, significantly faster than the approximate one week that it now takes between diagnosis and genetic analysis.
“Food security is an important global issue and the 100K Foodborne Pathogen Genome Project will accelerate our ability to rapidly diagnose infectious microorganisms and improve food safety. Kapa Biosystems is proud to play a role in such a large-scale collaboration with potential to positively impact human health,” said Maryke Appel, Ph.D., Technical Director at Kapa Biosystems. “The fact that we were selected for this project is a strong validation of the high performance and quality of our products.”
About UC Davis
For more than 100 years, UC Davis has been one place where people are bettering humanity and our natural world while seeking solutions to some of our most pressing challenges. Located near the state capital, UC Davis has more than 33,000 students, over 2,500 faculty and more than 21,000 staff, an annual research budget of over $750 million, a comprehensive health system and 13 specialized research centers. The university offers interdisciplinary graduate study and more than 100 undergraduate majors in four colleges — Agricultural and Environmental Sciences, Biological Sciences, Engineering, and Letters and Science. It also houses six professional schools — Education, Law, Management, Medicine, Veterinary Medicine and the Betty Irene Moore School of Nursing.
About Kapa Biosystems
Kapa Biosystems is a life science reagents supplier that employs proprietary, directed evolution technologies to optimize enzymes for PCR, real-time PCR, next-generation sequencing and molecular diagnostic applications. Kapa Biosystems offers a portfolio of best-in-class products containing novel enzymes that confer significant performance advantages when compared to traditional wild-type enzymes. The company is based in Wilmington, Massachusetts with a research, development and manufacturing facility in Cape Town, South Africa. For more information, please visit www.kapabiosystems.com.
KAPA is a trademark of Kapa Biosystems. All other brands may be trademarks of their respective holders. Kapa Biosystems’ products are for Research Use Only; not for use in diagnostic procedures.